HORDB

ID: hor004134
Uniprot ID: Q99P85
Protein name: Resistin-like alpha
Gene name: Retnla
Organism: Rattus norvegicus (Rat)
Family: Resistin/FIZZ family
Source: Animal
Expression: Highest levels in adipose tissue.
Disease: NA
Comments: NA
Taxonomy: Rattus (genus), Murinae (subfamily), Muridae (family), Muroidea, Myomorpha (suborder), Rodentia (order), Glires, Euarchontoglires (superorder), Boreoeutheria, Eutheria, Theria, Mammalia (class), Amniota, Tetrapoda, Dipnotetrapodomorpha, Sarcopterygii (superclass), Euteleostomi, Teleostomi, Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity
GO BP: GO:0007165 signal transduction
GO CC: GO:0005576 extracellular region; GO:0005615 extracellular space

Sequence: DGTLDIIGKKKVKELLAHQDNYPSAVRKTLSCTNVKSMSKWASCPAGMTATGCSCGFACGSWEIQNENICNCLCLIVDWAYARCCQLS
Length: 88(24-111)
Propeptide: MKTATCSLLICVFLLQLMVPVNTDGTLDIIGKKKVKELLAHQDNYPSAVRKTLSCTNVKSMSKWASCPAGMTATGCSCGFACGSWEIQNENICNCLCLIVDWAYARCCQLS
Signal peptide: MKTATCSLLICVFLLQLMVPVNT
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor004134_AF2.pdb

hor004134_ESM.pdb

Mass:	1110713	Formula:	C408H652N114O126S12
Absent amino acids:		Common amino acids:	C
pI:	7.86	Basic residues:	10
Polar residues:	36	Hydrophobic residues:	28
Hydrophobicity:	-1.02	Boman Index:	-9602
Half-Life:	1.1 hour	Half-Life Yeast:	3 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	75.45
Instability Index:	4431.14	Extinction Coefficient cystines:	20105
Absorbance 280nm:	231.09